| Lee
Anna Cunningham, Ph.D.
Professor Department of Neurosciences
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Education
and Honors:
B.S. Biology, University of Illinois, Urbana, IL; Ph.D. Anatomical Sciences,
University of Illinois; Postdoctoral Training, Department of Neurobiology and
Anatomy, University of Rochester, Rochester, NY
Research
Interests:
Neuron death, protection and repair in animal models of Parkinson's disease
and stroke: neurotrophins, astrocytes, stem cells, apoptosis, neurogenesis,
gene therapy
Current Publications:
Kokovay E, Cunningham LA (2005) Bone marrow-derived microglia contribute to the neuroinflammatory response and express iNOS in the MPTP mouse model of Parkinson’s disease. Neurobiology of Disease 19(3):471-8.
Cunningham, L.A., Wetzel, M., Rosenberg, G.A., (2005) Multiple roles for MMPs and Timps in cerebral ischemia. Glia 50:329-339.
Choi I, Allan AM, Cunningham LA, (2005) Moderate fetal alcohol exposure impairs the neurogenic response to an enriched environment in adult mice. Alcoholism: Clinical and Experimental Research 29: 2053.
Kokovay E, Lu L, Cunningham LA, (2006) Angiogenic recruitment of pericytes from bone marrow after stroke. Journal of Cerebral Blood Flow and Metabolism 26: 545
Wetzel M, Li L, Harms KM, Roitbak T, Ventura PB, Rosenberg GA, Khokha R, Cunningham LA, (2008) Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia. Cell Death and Differentiation 15: 143-151
Roitbak T, Li L, Cunningham LA, (2008) Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1alpha-regulated VEGF signaling. J Cereb Blood Flow Metab. 2008 May 14. 28:1530-1542.
Barkho, BZ, Munoz, A., Li, X, Li, L, Cunningham, LA, Zhao, X (2008) Endogenous matrix metalloproteinase (MMP)-3 and MMP-9 promote the differentiation and migration of adult neural progenitor cells in response to chemokines. Stem Cells. 2008 Dec;26(12):3139-49. Epub 2008 Sep 25.
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